Palladium-catalyzed late-stage mono-aroylation of the fully substituted pyrazoles via aromatic C-H bond activation

论文摘要

The palladium-catalyzed late-stage aroylation of 4-methyl-1,5-diaryl-lH-pyrazole-3-carboxylates has been developed via direct and exclusive mono-Csp2-H bond activation with broad substrate scope and good functional group tolerance. A dual-core dimeric palladacycle is confirmed by X-ray single crystal crystallography, and probably serves as an active species in the catalytic cycle.

论文目录

文章来源

类型: 期刊论文

作者: Miao-Miao Chen,Ling-Yan Shao,Li-Jun Lun,Yu-Liang Wu,Xiao-Pan Fu,Ya-Fei Ji

来源: Chinese Chemical Letters 2019年03期

年度: 2019

分类: 工程科技Ⅰ辑

专业: 化学

单位: School of Pharmacy, East China University of Science & Technology,Shandong Keyuan Pharmaceutical Co., Ltd., Shandong Shanghe Economic Development Zone

基金: the National Natural Science Foundation of China(Nos. 21476074 and 21676088)for financial support

分类号: O621.251

页码: 702-706

总页数: 5

文件大小: 552K

下载量: 8

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