论文摘要
Brain complexity is implemented by astounding diversity of cell types connected in approximate numbers and combinations.Thus, to define diverse neuronal cell types become increasingly appreciated as one of the most fundamental issue in brain science.As the key mediators,glutamatergic neurons are critical to transmit neuronal activities within the circuits.Here, we performed single-cell RNA sequencing of ～80,000 cells from 7 days-post fertilization larval zebrafish and mapped out dozens of glutamatergic neuron types across distinct major brain regions.Combined with the analysis of sparsely labeled single glutamatergic neurons of different subtypes,we made the further characterization of these subtypes for different aspects, including cell-body position, dendritic structure, axonal projection.Together, our study provides an enriched resource for whole-brain glutamatergic subtypes.
论文目录
文章来源
类型: 国内会议
作者: 何杰
来源: 2019中国生理学会学术年会暨张锡钧基金第十五届全国青年优秀生理学学术论文交流会及第十三届全国青年生理学工作者学术会议 2019-12-20
年度: 2019
分类: 基础科学
专业: 生物学
单位: 中国科学院神经科学研究所
分类号: Q421
DOI: 10.26914/c.cnkihy.2019.066164
页码: 130-131
总页数: 2
文件大小: 580k