Dichloromethane as a methylene synthon for regioselective linkage of diverse carboxylic acids:Direct access to methylene diesters under metal-free conditions

论文摘要

A metal-free cross coupling between common CH2Cl2 and carboxylic acids has been achieved with K2CO3 as the sole additive.This simple protocol is a co nvenient and cost-effective route to synthesize methylene diesters from a wide scope of carboxylic acids substrates with good functional group tolerance.Several gram-scale reactions have been performed to evaluate the effectiveness and practicality of this protocol.

论文目录

文章来源

类型: 期刊论文

作者: Shuiliang Wang,Zhengjiang Fu,Zhicong Huang,Yongqing Jiang,Shengmei Guo,Hu Cai

来源: Chinese Chemical Letters 2019年06期

年度: 2019

分类: 工程科技Ⅰ辑

专业: 化学

单位: College of Chemistry,Nanchang University,State Key Laboratory of Structural Chemistry,Fujian Institute of Research on the Structure of Matter,CAS

基金: Financial support from the National Natural Science Foundation of China(NSFC,Nos. 21761021 and 21571094),Natural Science Foundation of Jiangxi Province(No. 20171BAB203002),Sci & Tech Project of Education Department of Jiangxi Province(No. 60007)

分类号: O621.3

页码: 1173-1177

总页数: 5

文件大小: 385K

下载量: 8

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