NAD kinase sustains lipogenesis and mitochondrial metabolism

论文摘要

<正>Lipid storage in fat tissue is important for systemic energy homeostasis.Through RNAi screen in Drosophila fat body,we identified that knockdown of CG6145/NADK,encoding a cytosolic NAD kinase in Drosophila,causes lipid storage defect.NAD kinase and NADP(H).NADK sustains lipogenesis through maintaining the pool of NADPH.Promoting NADPH production by food

论文目录

文章来源

类型: 国内会议

作者: Mengyao Xu,Long Ding,Xiao Yang,Yuan Liu,Yingchun Wang,Mei Ding,Xun Huang

来源: 第三届中国生物物理学会代谢生物学分会学术研讨会 2019-05-10

年度: 2019

分类: 基础科学

专业: 生物学

单位: 遗传与发育生物学研究所,State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,University of Chinese Academy of Sciences

分类号: Q55

DOI: 10.26914/c.cnkihy.2019.051074

页码: 122+63

总页数: 2

文件大小: 58k

下载量: 1

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