Cryo-EM and molecular simulation study of glutamate receptor activation mechanism

论文摘要

<正>Cryo-electron microscopy and other imaging technique opened new windows to study large biomolecular assemblies under biologically relevant conditions. Ionotropic glutamate receptors（i GluRs） are cation channels that mediate signal transmission in the central nervous system by depolarizing the post-dynaptic membrane in response to L-glutamate release from the presynaptic neuron. GluA2 is a subunit ofα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid （AMPA）-sensitive ionotropic glutamate receptors, a major subtypes of i GluRs, which harbors a modular

论文目录

文章来源

类型: 国内会议

作者: 吴雄武

来源: 第六届全国冷冻电子显微学与结构生物学专题研讨会 2019-06-16

年度: 2019

分类: 基础科学

专业: 生物学

单位: Laboratory of Computational Biology, NHLBI,NIH

分类号: Q-336

DOI: 10.26914/c.cnkihy.2019.038773

页码: 29

总页数: 1

文件大小: 172k

下载量: 4

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